KMID : 0670820170220030087
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Korean Journal of Medical Mycology 2017 Volume.22 No. 3 p.87 ~ p.97
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Laser and Light Sources in the Treatment of Onychomycosis
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Nam Jae-Hui
Kim Jung-Yup
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Abstract
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Onychomycosis is a common fungal infection ofthe nails and there is widedistribution across the continent. Aside from Trichophyton rubrum (88%) being the main causative agent, otherdermatophytes, yeasts or non-dermatophyte molds can affect nails and adjacenttissues and cause sundry symptoms: subungual hyperkeratosis, onycholysis, nailthickening, discoloration, malodorous condition. Oral antifungal agents are themainstay treatment for onychomycosis but undesirable side effects, such ashepatotoxicity, remain a main reason for drug withdrawal. Moreover, othermodalities as a reliable treatment option are disappointing with a low curerate. The advancement in laser and light technology has opened a new field ofopportunity for thetreatment ofrefractory skin disease. As supported in clinical studies,neodymium-doped yttrium aluminium garnet laser, diode laser, fractional carbondioxide laser,and erbium:glass laser have produced a favorable outcome, with or withoutadditional agents, for the treatment ofonychomycosis. But themechanism is still unclear and reliable data are relatively scarce despite thepotential as an alternative armamentarium. To date, as with laser therapy,there have been only a few studies conducted concerning the role oflight therapy in thesuperficial fungal infection. Herein we aimed to review the medical literatureon laser and light therapy ofonychomycosis and provide our point ofview for health providersand researchers.
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KEYWORD
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Fungal infection, Laser, Light, Onychomycosis, Tinea unguium
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